Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4633591 | 0.86 | CYP19A1 (0.33) | GPR3CYP19A1 | |
| Hydrochloric Acid SCHEMBL10320324 | 0.83 | MEN1 (0.33) | GPR3POLB | |
| Hydrochloric Acid SCHEMBL10321197 | 0.83 | GPR3 (0.32) | GPR3 | |
| SCHEMBL28226566 | 0.80 | GPR3 (0.34) | GPR3HTR2APOLB | |
| SCHEMBL9602938 | 0.80 | GPR3 (0.34) | GPR3HTR2APOLB | |
| SCHEMBL9633188 | 0.80 | HPGD (0.36) | GPR3 | |
| SCHEMBL30390148 | 0.80 | GPR3 (0.46) | GPR3CYP19A1HTR2APOLBCHRM2 | |
| SCHEMBL6671925 | 0.80 | GPR3 (0.46) | GPR3CYP19A1HTR2APOLBCHRM2 | |
| Hydrochloric Acid SCHEMBL10317877 | 0.79 | CYP19A1 (0.31) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL8080602 | 0.79 | GPR3 (0.33) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191910-B | Mono-metallocene compound and preparation method thereof, catalyst composition for olefin polymerization and application thereof, and method for preparing propylene homopolymer | 中国石油化工股份有限公司 | 2020-11-10 | — | — | CN | disclosed |
| EP-1520862-B1 | Butadiene polymer, and process for producing conjugated diene polymer | AGENCY IND SCIENCE TECHN (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1520862-A2 | Butadiene polymer, and process for producing conjugated diene polymer | JAPAN as Represented by DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2005-04-06 | — | — | EP | disclosed |
| EP-1054026-B1 | BUTADIENE POLYMERS AND PROCESS FOR PRODUCING CONJUGATED DIENE POLYMERS | JP AGENCY OF INDUSTRIALSCIENCE (JP) | 2004-12-08 | — | — | EP | disclosed |
| US-6653430-B1 | Addition polymerizing in presence of Group 4 metal complex having cyclopentadienyl structure and alumoxane cocatalyst; high cis configuration | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2003-11-25 | — | — | US | disclosed |