SCHEMBL9633188

SCHEMBL9633188

C[Si](C)(C)C1c2ccccc2-c2cccc(Cl)c21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
RAB9A P51151 1/20 0.36
CACNB4 O00305 1/20 0.35
CACNA1A O00555 1/20 0.35
CACNA1G O43497 1/20 0.35
CACNG3 O60359 1/20 0.35
CACNA1F O60840 1/20 0.35
CACNA1H O95180 1/20 0.35
CACNB3 P54284 1/20 0.35
CACNA2D1 P54289 1/20 0.35
CACNG7 P62955 1/20 0.35
CACNA1B Q00975 1/20 0.35
CACNA1D Q01668 1/20 0.35
CACNB1 Q02641 1/20 0.35
CACNG1 Q06432 1/20 0.35
CACNB2 Q08289 1/20 0.35
CACNA1S Q13698 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4633144 0.80 GPR3 (0.35) GPR3
SCHEMBL9602938 0.79 GPR3 (0.34) GPR3ALDH1A1
SCHEMBL30390148 0.78 GPR3 (0.46) GPR3ALDH1A1
SCHEMBL6671925 0.78 GPR3 (0.46) GPR3ALDH1A1
Hydrochloric Acid SCHEMBL8080602 0.77 GPR3 (0.33) GPR3
SCHEMBL12429503 0.76 GPR3 (0.38) HPGDSMN1; SMN2CACNB4CACNA1ACACNA1G
Hydrochloric Acid SCHEMBL4633591 0.75 CYP19A1 (0.33) GPR3
SCHEMBL5618043 0.73 CACNB4 (0.39) HPGDSMN1; SMN2TP53CACNB4CACNA1A
SCHEMBL18242146 0.72 HTR7 (0.41) HPGDSMN1; SMN2TP53CACNB4CACNA1A
SCHEMBL1635439 0.72 HTR2B (0.51) HPGDSMN1; SMN2TP53CACNB4CACNA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5101059-A Xanthene compounds RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-03-31 US disclosed
WO-1991008190-A1 AMINO ACID PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO disclosed