Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395477 | 0.89 | GPR119 (0.38) | GPR119ALDH1A1 | |
| SCHEMBL4409824 | 0.78 | GPR119 (0.40) | GPR119ALDH1A1 | |
| SCHEMBL4764791 | 0.75 | AKR1B10 (0.33) | SMN1; SMN2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL4397750 | 0.72 | GPR119 (0.43) | GPR119TRPV1CHRM2CHRM1SMN1; SMN2 | |
| SCHEMBL7396050 | 0.68 | KMT2A (0.50) | GPR119SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL4412237 | 0.67 | PLK1 (0.54) | GPR119 | |
| SCHEMBL14029675 | 0.66 | PLK1 (0.38) | ALDH1A1 | |
| SCHEMBL4661126 | 0.65 | MAPT (0.52) | SMN1; SMN2ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL23466891 | 0.65 | PDE4B (0.45) | GPR119CHRM2CHRM1SMN1; SMN2MMP13 | |
| SCHEMBL4404192 | 0.64 | MAPT (0.37) | SMN1; SMN2ALDH1A1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924572-A1 | REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES | SmithKline Beecham Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007030366-A1 | REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |