Styrene

Styrene

SCHEMBL4633239

C=Cc1ccccc1.C=Cc1ccccc1C=C.OC=Cc1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
TSHR P16473 1/20 0.56
TRPA1 O75762 2/20 0.44
NFE2L2 Q16236 3/20 0.39
MAOB P27338 1/20 0.39
MAPT P10636 2/20 0.38
RECQL P46063 2/20 0.38
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360362 0.96 ALDH1A1 (0.48) ALDH1A1TSHRTRPA1NFE2L2MAOB
Styrene SCHEMBL546105 0.92 ALDH1A1 (0.67) ALDH1A1TSHRTRPA1NFE2L2MAOB
Styrene SCHEMBL7904441 0.85 ALDH1A1 (0.78) ALDH1A1TSHRTRPA1NFE2L2MAOB
Styrene SCHEMBL15656 0.85 ALDH1A1 (0.78) ALDH1A1TSHRTRPA1NFE2L2MAOB
SCHEMBL1635567 0.85 TRPA1 (0.60) ALDH1A1TSHRTRPA1NFE2L2MAOB
SCHEMBL14685993 0.83 ALDH1A1 (0.64) ALDH1A1TSHRTRPA1NFE2L2MAOB
Styrene SCHEMBL4994871 0.83 ALDH1A1 (0.74) ALDH1A1TSHRTRPA1NFE2L2MAOB
(Z)-1,2-Diphenylethene SCHEMBL10982590 0.83 ALDH1A1 (0.57) ALDH1A1TSHRTRPA1NFE2L2MAOB
Styrene SCHEMBL3475213 0.83 ALDH1A1 (0.74) ALDH1A1TSHRTRPA1NFE2L2MAOB
Styrene SCHEMBL16765688 0.83 ALDH1A1 (0.74) ALDH1A1TSHRTRPA1NFE2L2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1595895-B1 Production method of porous resin NITTO DENKO CORP (JP) 2008-05-28 EP claimed
EP-1510541-B1 Porous resin bead and production method thereof NITTO DENKO CORP (JP) 2007-02-14 EP claimed