SCHEMBL4633347

SCHEMBL4633347

CCCC(C)C(O)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.45
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.40
ALDH1A1 P00352 1/20 0.38
METAP1 P53582 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10596365 1.00 GPR84 (0.45) GPR84HDAC1HDAC2CHRM1AKR1A1
SCHEMBL10599123 1.00 GPR84 (0.45) GPR84HDAC1HDAC2CHRM1AKR1A1
SCHEMBL4744405 0.87 GPR84 (0.52) GPR84ALDH1A1FFAR4FFAR1
SCHEMBL667414 0.87 GPR84 (0.52) GPR84ALDH1A1FFAR4FFAR1
SCHEMBL17113879 0.85 GPR84 (0.60) GPR84MAPTFFAR4FFAR1
SCHEMBL4957082 0.84 GPR84 (0.63) GPR84TDP1SLC22A6ALDH1A1MAPT
SCHEMBL1483983 0.84 GPR84 (0.63) GPR84TDP1SLC22A6ALDH1A1MAPT
SCHEMBL17867252 0.82 SLC22A6 (0.40) GPR84ADRA1ATDP1SLC22A6SMN1; SMN2
SCHEMBL2988034 0.82 GPR84 (0.45) GPR84HDAC1HDAC2CHRM1AKR1A1
SCHEMBL16600585 0.81 GPR84 (0.48) GPR84HDAC1HDAC2CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015144485-A1 OLFACTORY BOOSTERS HENKEL AG & CO. KGAA (DE) 2015-10-01 WO claimed
WO-2015144485-A1 OLFACTORY BOOSTERS HENKEL AG & CO. KGAA (DE) 2015-10-01 WO disclosed
US-20080260670-A1 Organic Compounds GIVAUDAN SA (CH) 2008-10-23 US disclosed
CN-101267860-A Organic compounds GIVAUDAN SA (CH) 2008-09-17 CN disclosed
EP-1926531-A2 ORGANIC COMPOUNDS Givaudan SA (CH) 2008-06-04 EP disclosed
EP-1841472-A2 BIODEGRADABLE COATING COMPOSITIONS INCLUDING MULTIPLE LAYERS SurModics, Inc. (US) 2007-10-10 EP disclosed
EP-1838363-A2 BIODEGRADABLE COATING COMPOSITIONS COMPRISING BLENDS SurModics, Inc. (US) 2007-10-03 EP disclosed
WO-2007033508-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2007-03-29 WO disclosed
US-20060198868-A1 Biodegradable coating compositions comprising blends Surmodics Coatings, LLC 2006-09-07 US disclosed
WO-2006074406-A2 BIODEGRADABLE COATING COMPOSITIONS INCLUDING MULTIPLE LAYERS SURMODICS, INC. (US) 2006-07-13 WO disclosed
US-5152781-A Bioresorbable and biodurable polycarbonate biopolymers ALLIED-SIGNAL INC. (US) 1992-10-06 US disclosed
US-5145945-A Biocompatable ALLIED-SIGNAL INC. (US) 1992-09-08 US disclosed
US-5120802-A Fibers and bioresorbable implants ALLIED-SIGNAL INC. (US) 1992-06-09 US disclosed
EP-0390860-A4 MEDICAL DEVICES FABRICATED FROM HOMOPOLYMERS AND COPOLYMERS HAVING RECURRING CARBONATE UNITS 1991-06-12 EP disclosed
EP-0390860-A1 MEDICAL DEVICES FABRICATED FROM HOMOPOLYMERS AND COPOLYMERS HAVING RECURRING CARBONATE UNITS. ALLIED SIGNAL INC (US) 1990-10-10 EP disclosed
US-4920203-A Medical devices fabricated from homopolymers and copolymers having recurring carbonate units ALLIED-SIGNAL INC. (US) 1990-04-24 US disclosed
US-4891263-A DIODERGRADABLE ALLIED-SIGNAL INC. (US) 1990-01-02 US disclosed
US-4864056-A METHYL 3-HYDROXY-2,4-DIMETHYLHEPTANOATE NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-09-05 US disclosed
WO-1989005664-A1 MEDICAL DEVICES FABRICATED FROM HOMOPOLYMERS AND COPOLYMERS HAVING RECURRING CARBONATE UNITS ALLIED-SIGNAL INC. (US) 1989-06-29 WO disclosed
US-4835292-A Novel optically active alcohol NITTO ELECTRIC INDUSTRIAL (JP) 1989-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080260670-A1 Organic Compounds OR10J3, OR51E2, ELOVL1 GPR84 435/4885HDAC1 1185/4885HDAC2 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.