SCHEMBL2988034

SCHEMBL2988034

CCCC(O)C(C)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.45
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.40
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175092 0.87 GPR84 (0.52) GPR84FFAR4FFAR1NFKB1
SCHEMBL28237272 0.87 GPR84 (0.52) GPR84FFAR4FFAR1NFKB1
SCHEMBL16230502 0.85 GPR84 (0.60) GPR84MAPTFFAR4FFAR1NFKB1
SCHEMBL16230501 0.85 GPR84 (0.60) GPR84MAPTFFAR4FFAR1NFKB1
SCHEMBL5575674 0.85 GPR84 (0.60) GPR84MAPTFFAR4FFAR1NFKB1
SCHEMBL19611417 0.84 GPR84 (0.63) GPR84SLC22A6ALDH1A1LMNAMAPT
SCHEMBL28284749 0.84 GPR84 (0.63) GPR84SLC22A6ALDH1A1LMNAMAPT
SCHEMBL4633347 0.82 GPR84 (0.45) GPR84HDAC1HDAC2CHRM1AKR1A1
SCHEMBL10599123 0.82 GPR84 (0.45) GPR84HDAC1HDAC2CHRM1AKR1A1
SCHEMBL10596365 0.82 GPR84 (0.45) GPR84HDAC1HDAC2CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074518-B1 RESIN COMPOSITION, RESIN-METAL COMPOSITE MEMBER, AND TIRE BRIDGESTONE CORP (JP) 2023-10-18 EP disclosed
EP-3608128-B1 RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORP (JP) 2023-09-27 EP disclosed
EP-3702174-B1 METAL RESIN COMPOSITE MEMBER FOR TIRES, AND TIRE BRIDGESTONE CORP (JP) 2023-05-17 EP disclosed
US-20230023212-A1 RESIN COMPOSITION, RESIN-METAL COMPOSITE MEMBER, AND TIRE BRIDGESTONE CORPORATION (JP) 2023-01-26 US disclosed
EP-4074518-A1 RESIN COMPOSITION, RESIN/METAL COMPOSITE MEMBER, AND TIRE BRIDGESTONE CORPORATION (JP) 2022-10-19 EP disclosed
EP-3611033-B1 TIRE, AND METHOD FOR MANUFACTURING TIRE BRIDGESTONE CORP (JP) 2022-05-04 EP disclosed
EP-3640049-B1 RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORP (JP) 2022-02-23 EP disclosed
US-20220033644-A1 RESIN COMPOSITION FOR TIRE, RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2022-02-03 US disclosed
EP-3640051-B1 RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORP (JP) 2022-01-05 EP disclosed
US-11135875-B2 Resin-metal composite member for tire, and tire BRIDGESTONE CORPORATION (JP) 2021-10-05 US disclosed
CN-104144801-A Tire BRIDGESTONE CORP 2014-11-12 CN disclosed
US-20100291168-A1 ANTIMICROBIAL FORMULATIONS COMPRISING A COMBINATION OF A PYRIDINE THIOL AND A BIS-QUINOLINIUM SALT SYNTOPIX GROUP PLC (GB) 2010-11-18 US disclosed
US-20100273876-A1 ANTIBACTERIAL FORMULATION COMPRISING A DIALKYL SULPHOSUCCINATE AND A CARBANILIDE ANTIBACTERIAL AGENT DOW PHARMACEUTICAL SCIENCES, INC. 2010-10-28 US disclosed
US-20100172854-A1 ANTIBACTERIAL FORMULATIONS SYNTOPIX GROUP PLC. (GB) 2010-07-08 US disclosed
EP-2152264-A1 ANTIMICROBIAL FORMULATIONS COMPRISING A COMBINATION OF A PYRIDINE THIOL AND A BIS-QUINOLINIUM SALT Syntopix Group plc (GB) 2010-02-17 EP disclosed
EP-2152260-A1 AN ANTIBACTERIAL FORMULATION COMPRISING A DIALKYL SULPHOSUCCINATE AND A CARBANILIDE ANTIBACTERIAL AGENT Syntopix Group plc (GB) 2010-02-17 EP disclosed
EP-2120903-A1 ANTIBACTERIAL FORMULATIONS Syntopix Group plc (GB) 2009-11-25 EP disclosed
WO-2008149089-A1 ANTIMICROBIAL FORMULATIONS COMPRISING A COMBINATION OF A PYRIDINE THIOL AND A BIS-QUINOLINIUM SALT SYNTOPIX LIMITED (GB) 2008-12-11 WO disclosed
WO-2008146030-A1 AN ANTIBACTERIAL FORMULATION COMPRISING A DIALKYL SULPHOSUCCINATE AND A CARBANILIDE ANTIBACTERIAL AGENT SYNTOPIX LIMITED (GB) 2008-12-04 WO disclosed
WO-2008113981-A1 ANTIBACTERIAL FORMULATIONS SYNTOPIX LIMITED (GB) 2008-09-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100172854-A1 ANTIBACTERIAL FORMULATIONS CUTA, POLR1C, TAS2R3 GPR84 1611/4885HDAC1 1064/4885HDAC2 2250/4885
US-20100291168-A1 ANTIMICROBIAL FORMULATIONS COMPRISING A COMBINATION OF A PYRIDINE THIOL AND A BIS-QUINOLINIUM SALT SQOR, TST, QSOX1 GPR84 2382/4885HDAC1 1884/4885HDAC2 4297/4885
US-20100273876-A1 ANTIBACTERIAL FORMULATION COMPRISING A DIALKYL SULPHOSUCCINATE AND A CARBANILIDE ANTIBACTERIAL AGENT DEK, TAS2R10, ACMSD GPR84 828/4885HDAC1 2359/4885HDAC2 4154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.