Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3769291 | 0.84 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL19887751 | 0.69 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL19887771 | 0.69 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL3762637 | 0.69 | P2RX7 (0.37) | P2RX7TTR | |
| SCHEMBL8190076 | 0.67 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL4632389 | 0.67 | TAAR1 (0.41) | P2RX7HCAR2TTR | |
| SCHEMBL4633267 | 0.66 | DBH (0.34) | P2RX7HCAR2TTR | |
| SCHEMBL10335750 | 0.65 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL12646239 | 0.65 | SLC5A2 (0.36) | — | |
| SCHEMBL12810062 | 0.64 | P2RX7 (0.33) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912656-A2 | METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES | Boehringer Ingelheim International GmbH (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007014895-A2 | METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-08 | — | — | WO | disclosed |