Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770602 | 0.83 | TAAR1 (0.42) | TAAR1GRK6TTRP2RX7MEN1 | |
| SCHEMBL4633267 | 0.80 | DBH (0.34) | TTRSMPD3HCAR2ADORA2AP2RX7 | |
| SCHEMBL13073165 | 0.69 | TAAR1 (0.63) | TAAR1USP7KMT2ATRAP1HSP90B1 | |
| SCHEMBL3779266 | 0.68 | ALDH1A1 (0.42) | P2RX7MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4633441 | 0.67 | P2RX7 (0.40) | TTRHCAR2P2RX7 | |
| SCHEMBL3769458 | 0.65 | MAPT (0.41) | ADORA2AADORA1MEN1GAAKMT2A | |
| SCHEMBL3776543 | 0.64 | TAAR1 (0.61) | TAAR1ALDH1A1 | |
| SCHEMBL16518659 | 0.63 | TAAR1 (0.55) | TAAR1USP7TRAP1ALDH1A1HPGD | |
| SCHEMBL13548269 | 0.63 | TAAR1 (0.70) | TAAR1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL16693753 | 0.62 | TAAR1 (0.53) | TAAR1USP7MEN1KMT2ATRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912656-A2 | METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES | Boehringer Ingelheim International GmbH (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007014895-A2 | METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-08 | — | — | WO | disclosed |