Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930496 | 0.93 | TSHR (0.48) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL930150 | 0.91 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL24855609 | 0.91 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL3025339 | 0.90 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL929719 | 0.88 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL12947807 | 0.87 | CASP2 (0.68) | CASP2NAAADNM1FAAH | |
| SCHEMBL12605287 | 0.86 | CNR1 (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL929190 | 0.86 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9128874 | 0.86 | SLC6A5 (0.51) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL15058758 | 0.86 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | claimed |