Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929719 | 0.92 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL930496 | 0.92 | TSHR (0.48) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4633503 | 0.90 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9649999 | 0.88 | CNR1 (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL12605287 | 0.86 | CNR1 (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL12231859 | 0.86 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL24855609 | 0.85 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL929190 | 0.85 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13317011 | 0.84 | CASP2 (0.59) | TSHRDNM1FAAHCASP2 | |
| SCHEMBL12231862 | 0.84 | TSHR (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100209373-A1 | DITHIOLS AND USE THEREOF FOR STRENGTHENING THE HAIR | L'OREAL S.A. (FR) | 2010-08-19 | — | — | US | claimed |
| US-20050019290-A1 | Dithiols and use thereof for strengthening the hair | L'OREAL S.A. (FR) | 2005-01-27 | — | — | US | claimed |
| US-20050002886-A1 | Dithiols comprising at least one amide functional group and their use in transforming the shape of the hair | L'OREAL S.A. (FR) | 2005-01-06 | — | — | US | claimed |
| EP-1477158-A1 | Dithiols and their use to strenghten the hair | L'OREAL (FR) | 2004-11-17 | — | — | EP | claimed |
| US-20100209373-A1 | DITHIOLS AND USE THEREOF FOR STRENGTHENING THE HAIR | L'OREAL S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| US-20100209373-A1 | DITHIOLS AND USE THEREOF FOR STRENGTHENING THE HAIR | L'OREAL S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| US-20100209373-A1 | DITHIOLS AND USE THEREOF FOR STRENGTHENING THE HAIR | L'OREAL S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| US-20050019290-A1 | Dithiols and use thereof for strengthening the hair | L'OREAL S.A. (FR) | 2005-01-27 | — | — | US | disclosed |
| US-20050002886-A1 | Dithiols comprising at least one amide functional group and their use in transforming the shape of the hair | L'OREAL S.A. (FR) | 2005-01-06 | — | — | US | disclosed |
| EP-1477158-A1 | Dithiols and their use to strenghten the hair | L'OREAL (FR) | 2004-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209373-A1 | DITHIOLS AND USE THEREOF FOR STRENGTHENING THE HAIR | KRT18, DSG1, DSP | HDAC3 2687/4885HDAC1 1927/4885HDAC2 2706/4885 |
| US-20050002886-A1 | Dithiols comprising at least one amide functional group and their use in transforming the shape of the hair | TST, KRT18, DLAT | HDAC3 666/4885HDAC1 234/4885HDAC2 581/4885 |
| US-20050019290-A1 | Dithiols and use thereof for strengthening the hair | KRT18, DSG1, DSP | HDAC3 2687/4885HDAC1 1927/4885HDAC2 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.