Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 10/20 | 0.57 |
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.52 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622444 | 0.81 | MEN1 (0.73) | KDM4EKMT2AMEN1TSHRNPC1 | |
| SCHEMBL4633514 | 0.80 | KMT2A (0.64) | KDM4EKMT2AMEN1TSHRNPC1 | |
| SCHEMBL3617391 | 0.80 | KDM4E (1.00) | KDM4EKMT2AMEN1TSHRNPC1 | |
| SCHEMBL4633510 | 0.78 | KMT2A (0.65) | KDM4EKMT2AMEN1TSHRNPC1 | |
| SCHEMBL29035358 | 0.73 | NPC1 (0.45) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL28397771 | 0.71 | L3MBTL1 (0.63) | KDM4EKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13617121 | 0.71 | HPGD (0.48) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL8244239 | 0.71 | KDM4E (0.62) | KDM4EKMT2AMEN1TSHRNPC1 | |
| SCHEMBL23934267 | 0.71 | HPGD (0.53) | KDM4EKMT2AMEN1TSHRNPC1 | |
| SCHEMBL23934282 | 0.70 | KDM4E (0.59) | KDM4EKMT2AMEN1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |