Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | SENP5 | Q96HI0 | 7/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 7/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 7/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634471 | 0.87 | KMT2A (0.50) | FFAR1AKR1B1PTPN1EGLN1LMNA | |
| SCHEMBL4632905 | 0.86 | ALDH1A1 (0.43) | LMNAALDH1A1KMT2AGAAMAPT | |
| SCHEMBL4634428 | 0.84 | ALDH1A1 (0.43) | FFAR1LMNAALDH1A1KMT2AGAA | |
| SCHEMBL4633948 | 0.83 | KMT2A (0.54) | LMNAALDH1A1KMT2AGAAMAPT | |
| SCHEMBL4632910 | 0.83 | KMT2A (0.52) | LMNAALDH1A1KMT2AGAAMAPT | |
| SCHEMBL4633605 | 0.81 | FFAR1 (0.53) | FFAR1AKR1B1PTPN1EGLN1ALDH1A1 | |
| SCHEMBL4635042 | 0.81 | MAPT (0.50) | LMNAALDH1A1KMT2AGAAMAPT | |
| SCHEMBL4634028 | 0.81 | SENP5 (0.46) | LMNAALDH1A1KMT2AGAAMAPT | |
| SCHEMBL4632951 | 0.80 | FFAR1 (0.45) | FFAR1LMNAALDH1A1KMT2AGAA | |
| SCHEMBL4633910 | 0.79 | ALDH1A1 (0.47) | FFAR1LMNAALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |