Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634942 | 0.85 | KMT2A (0.60) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4632910 | 0.84 | KMT2A (0.52) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4633589 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4634428 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4634000 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4633948 | 0.80 | KMT2A (0.54) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4633019 | 0.79 | PTPN2 (0.48) | ALDH1A1LMNAFFAR4FFAR1SENP5 | |
| SCHEMBL4633522 | 0.79 | FFAR1 (0.46) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4634993 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL4635043 | 0.79 | CXCR2 (0.55) | ALDH1A1KMT2ALMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |