Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453239 | 0.93 | HDAC6 (0.64) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL3455667 | 0.89 | GAA (0.57) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL31612305 | 0.85 | PRSS1 (0.51) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL9491686 | 0.83 | NPC1 (0.75) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL8779817 | 0.83 | HDAC1 (0.79) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL5528994 | 0.82 | NAAA (0.51) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL9489804 | 0.81 | HDAC1 (0.82) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL9188890 | 0.81 | HDAC1 (0.82) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL20734829 | 0.81 | HDAC1 (0.82) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL7460068 | 0.81 | HDAC1 (0.82) | NPC1RAB9AHDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776308-A | A kind of synthetic method of N- (3- cyanopropyl) Carbox amide | 河南师范大学 | 2019-05-21 | — | — | CN | disclosed |
| EP-1928863-A2 | PHARMACEUTICAL DOSAGE FORMS AND COMPOSITIONS COMPRISING LECOZTAN | Wyeth a Corporation of the State of Delaware (US) | 2008-06-11 | — | — | EP | disclosed |
| US-20070099931-A1 | Pharmaceutical dosage forms and compositions | WYETH (US) | 2007-05-03 | — | — | US | disclosed |
| WO-2007030589-A2 | PHARMACEUTICAL DOSAGE FORMS AND COMPOSITIONS COMPRISING LECOZTAN | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |
| EP-1730139-A2 | PHARMACEUTICAL DOSAGE FORMS AND COMPOSITIONS OF 5-HT1A RECEPTOR ANTAGONISTS | Wyeth (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092307-A2 | PHARMACEUTICAL DOSAGE FORMS AND COMPOSITIONS OF 5-HT1A RECEPTOR ANTAGONISTS | WYETH (US) | 2005-10-06 | — | — | WO | disclosed |
| US-20050215561-A1 | Pharmaceutical dosage forms and compositions | WYETH LLC | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099931-A1 | Pharmaceutical dosage forms and compositions | CYP4B1, CYP1B1, CFTR | NPC1 262/4885RAB9A 4276/4885HDAC1 2120/4885 |
| US-20050215561-A1 | Pharmaceutical dosage forms and compositions | CFTR, CYP4B1, CYP1B1 | NPC1 156/4885RAB9A 4057/4885HDAC1 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.