Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | SENP5 | Q96HI0 | 5/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604066 | 0.89 | SENP5 (0.44) | ALDH1A1FFAR1FFAR4SENP5SENP2 | |
| SCHEMBL4634942 | 0.86 | KMT2A (0.60) | KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL4605093 | 0.81 | PDE10A (0.41) | FFAR1FFAR4SENP5SENP2SENP1 | |
| SCHEMBL4634951 | 0.81 | KDM4E (0.67) | PTPN2PTPN1KDM4EALDH1A1SENP5 | |
| SCHEMBL4632956 | 0.80 | FFAR1 (0.46) | PTPN2PTPN1KDM4EALDH1A1MCL1 | |
| SCHEMBL4635097 | 0.80 | PTPN2 (0.46) | PTPN2PTPN1KDM4EALDH1A1MCL1 | |
| SCHEMBL4633910 | 0.79 | ALDH1A1 (0.47) | ALDH1A1FFAR1FFAR4SENP5SENP2 | |
| SCHEMBL4633967 | 0.78 | HSD11B1 (0.46) | PTPN2PTPN1KDM4EALDH1A1MCL1 | |
| SCHEMBL4633605 | 0.77 | FFAR1 (0.53) | PTPN2PTPN1KDM4EALDH1A1FFAR1 | |
| SCHEMBL15697532 | 0.76 | PTPN2 (0.56) | PTPN2PTPN1KDM4EALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |