Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621443 | 0.87 | F10 (0.42) | GCGRF10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4666957 | 0.86 | LMNA (0.38) | F10RAB9ANPC1SMN1; SMN2BACE1 | |
| SCHEMBL4663209 | 0.85 | F10 (0.42) | F10RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8242181 | 0.85 | F10 (0.44) | GCGRF10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4667932 | 0.81 | F10 (0.43) | F10RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL5236615 | 0.78 | F10 (0.37) | F10RAB9ANPC1KLKB1MAPT | |
| SCHEMBL3621990 | 0.77 | LMNA (0.40) | F10RAB9ANPC1SMN1; SMN2BACE1 | |
| SCHEMBL5237942 | 0.77 | F10 (0.36) | F10RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL4665046 | 0.76 | F10 (0.42) | F10RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL4666914 | 0.76 | F10 (0.48) | F10MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |