Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 10/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | IL6ST | P40189 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17241987 | 0.87 | IDH1 (0.45) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL17241988 | 0.87 | IDH1 (0.45) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL8555425 | 0.87 | IDH1 (0.45) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL8883087 | 0.87 | IDH1 (0.45) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL12833452 | 0.85 | IDH1 (0.38) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL1049820 | 0.85 | NAAA (0.46) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL2029159 | 0.85 | NAAA (0.46) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL1049822 | 0.85 | NAAA (0.46) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL19815430 | 0.85 | FAAH (0.40) | IDH1NAAAIL6STPPARAFAAH | |
| SCHEMBL3650339 | 0.85 | NAAA (0.40) | IDH1NAAAIL6STPPARAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |