Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634570 | 1.00 | MAPT (0.54) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL18424657 | 0.79 | MAPT (0.40) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL18424658 | 0.79 | MAPT (0.40) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL3837967 | 0.78 | MEN1 (0.60) | MAPTPOLBTDP1MEN1LMNA | |
| SCHEMBL18612947 | 0.78 | MAPT (0.43) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL5600046 | 0.77 | ALDH1A1 (0.43) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL9658750 | 0.77 | KDM4E (0.42) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL5745015 | 0.76 | MAPT (0.39) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL6254793 | 0.76 | MAPT (0.39) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL9380523 | 0.76 | MAPT (0.41) | MAPTKDM4EPOLBTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1524261-B1 | Process for preparing fluorinated anilines | SALTIGO GMBH (DE) | 2008-06-11 | — | — | EP | claimed |
| US-7154006-B2 | Preparation of fluorinated anilines | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | claimed |
| US-20050101795-A1 | Preparation of fluorinated anilines | BAYER CHEMICALS AG | 2005-05-12 | — | — | US | claimed |
| EP-1524261-A1 | Process for preparing fluorinated anilines | Bayer Chemicals AG (DE) | 2005-04-20 | — | — | EP | claimed |
| EP-1524261-B1 | Process for preparing fluorinated anilines | SALTIGO GMBH (DE) | 2008-06-11 | — | — | EP | disclosed |
| US-7154006-B2 | Preparation of fluorinated anilines | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | disclosed |
| US-20050101795-A1 | Preparation of fluorinated anilines | BAYER CHEMICALS AG | 2005-05-12 | — | — | US | disclosed |
| EP-1524261-A1 | Process for preparing fluorinated anilines | Bayer Chemicals AG (DE) | 2005-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101795-A1 | Preparation of fluorinated anilines | FLNA, FLNB, FLI1 | MAPT 2465/4885KDM4E 2215/4885POLB 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.