Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254793 | 1.00 | MAPT (0.39) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL18424658 | 0.83 | MAPT (0.40) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL18424657 | 0.83 | MAPT (0.40) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL4634570 | 0.76 | MAPT (0.54) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL4634569 | 0.76 | MAPT (0.54) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL7498934 | 0.68 | KDM4E (0.38) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL7498929 | 0.68 | KDM4E (0.38) | MAPTKDM4EPOLBTHRBRECQL | |
| SCHEMBL5746321 | 0.67 | GAA (0.34) | MAPTKDM4ETHRBL3MBTL1MAPK1 | |
| SCHEMBL5746317 | 0.67 | GABRP (0.33) | KDM4EL3MBTL1MRGPRX4GAAALDH1A1 | |
| SCHEMBL9145901 | 0.66 | MRGPRX4 (0.59) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094906-B2 | Processes for preparing pesticidal intermediates | Basf Agro B.V. Arnthem (NL) Wädenswil-Branch (CH) | 2006-08-22 | — | — | US | disclosed |
| EP-0952145-B1 | Process for preparing pesticidal intermediates | BASF AGRO BV (CH) | 2005-10-05 | — | — | EP | disclosed |
| EP-1073627-B1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | BAYER AGRICULTURE LTD (GB) | 2004-12-01 | — | — | EP | disclosed |
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | AVENTIS AGRICULTURE LTD. (GB) | 2004-10-07 | — | — | US | disclosed |
| CN-1158249-C | Processes for preparing pesticidal intermediates | ��������ũҵ�� | 2004-07-21 | — | — | CN | disclosed |
| US-6673956-B2 | INTERMEDIATES (PARTICULARLY 2-(ARYLHYDRAZINO)SUCCINONITRILE COMPOUNDS AND 3-(ARYLHYDRAZONO)PROPIONITRILE DERIVATIVES FOR PESTICIDES, BY REACTING DIALKOXYPROPIONITRILE WITH AN ACID ADDITION SALT OF ARYLHYDRAZINE | AVENTIS AGRICULTURE LTD. (GB) | 2004-01-06 | — | — | US | disclosed |
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | MERIAL LIMITED | 2002-09-12 | — | — | US | disclosed |
| US-6392081-B1 | REACTING A NITRILE COMPOUND CONTAINING ACTAL GROUPS WITH ARYLHYDRAZINE; OXIDATION | AVENTIS AGRICULTURE LTD. (GB) | 2002-05-21 | — | — | US | disclosed |
| CN-1297429-A | Process for preparing pesticidal intermediates | AFANTI AGRICULTURE LTD (GB) | 2001-05-30 | — | — | CN | disclosed |
| EP-1073627-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054288-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 1999-10-28 | — | — | WO | disclosed |
| EP-0952145-A1 | Process for preparing pesticidal intermediates | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | SFXN3, SFXN1, CYP4F3 | MAPT 4852/4885KDM4E 2574/4885POLB 3307/4885 |
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | CBR3, HCN1, SF3A3 | MAPT 4862/4885KDM4E 2527/4885POLB 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.