Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRAT | P43155 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL319664 | 0.85 | CA1 (0.50) | CA1SLC22A16BBOX1CA4TP53 | |
| Acetic Acid SCHEMBL3015309 | 0.82 | CA1 (0.47) | CA1SLC22A16BBOX1CA4TP53 | |
| SCHEMBL159368 | 0.80 | ALDH1A1 (0.42) | TSHR | |
| Hydrochloric Acid SCHEMBL1041197 | 0.77 | ALDH1A1 (0.39) | — | |
| Water SCHEMBL721956 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL8406832 | 0.77 | ALDH1A1 (0.39) | — | |
| Acetic Acid SCHEMBL11574110 | 0.77 | — | — | |
| Iodide SCHEMBL17865373 | 0.77 | ALDH1A1 (0.39) | — | |
| Fluoride Ion SCHEMBL190627 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL5046885 | 0.77 | MEN1 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548575-A1 | ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES | Momentive Performance Materials Inc. (US) | 2019-10-09 | — | — | EP | claimed |
| WO-2018102510-A1 | ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-06-07 | — | — | WO | claimed |
| US-20180148601-A1 | ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-05-31 | — | — | US | claimed |
| US-11939490-B2 | Curable surface-protective coating composition, processes for its preparation and application to a metallic substrate and resulting coated metallic substrate | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2024-03-26 | — | — | US | disclosed |
| US-11370937-B2 | Protective coating composition and coated metallic substrate comprising same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2022-06-28 | — | — | US | disclosed |
| EP-3935114-A1 | PROTECTIVE COATING COMPOSITION AND COATED METALLIC SUBSTRATE COMPRISING SAME | Momentive Performance Materials Inc. (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3935115-A1 | PROTECTIVE COATING COMPOSITION AND COATED METALLIC SUBSTRATE COMPRISING SAME | Momentive Performance Materials Inc. (US) | 2022-01-12 | — | — | EP | disclosed |
| US-10968351-B2 | Thermal conducting silicone polymer composition | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-10941251-B2 | Silicone polymer and composition comprising the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2021-03-09 | — | — | US | disclosed |
| EP-3768763-A1 | SILICONE POLYMER AND COMPOSITION COMPRISING THE SAME | Momentive Performance Materials Inc. (US) | 2021-01-27 | — | — | EP | disclosed |
| EP-3768779-A1 | A THERMAL CONDUCTING SILICONE POLYMER COMPOSITION | Momentive Performance Materials Inc. (US) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019182860-A1 | SILICONE POLYMER AND COMPOSITION COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019182854-A1 | A THERMAL CONDUCTING SILICONE POLYMER COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019027991-A1 | CURABLE SURFACE-PROTECTIVE COATING COMPOSITION, PROCESSES FOR ITS PREPARATION AND APPLICATION TO A METALLIC SUBSTRATE AND RESULTING COATED METALLIC SUBSTRATE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-02-07 | — | — | WO | disclosed |
| US-20190031918-A1 | CURABLE SURFACE-PROTECTIVE COATING COMPOSITION, PROCESSES FOR ITS PREPARATION AND APPLICATION TO A METALLIC SUBSTRATE AND RESULTING COATED METALLIC SUBSTRATE | MOMENTIVE PERFORMANCE MATERIALS INC. | 2019-01-31 | — | — | US | disclosed |
| WO-2018102510-A1 | ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-06-07 | — | — | WO | disclosed |
| US-20180148601-A1 | ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-05-31 | — | — | US | disclosed |
| EP-1663486-A4 | LOW-ODOR CATALYST FOR ISOCYANATE-DERIVED FOAMS AND ELASTOMERS | HUNTSMAN SPEC CHEM CORP (US) | 2008-06-11 | — | — | EP | disclosed |
| EP-1663486-A2 | LOW-ODOR CATALYST FOR ISOCYANATE-DERIVED FOAMS AND ELASTOMERS | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005009601-A2 | LOW-ODOR CATALYST FOR ISOCYANATE-DERIVED FOAMS AND ELASTOMERS | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941251-B2 | Silicone polymer and composition comprising the same | H1-0, OR10J3, H1-2 | CA1 2000/4885SLC22A16 404/4885BBOX1 2516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.