Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 6/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635067 | 0.80 | HSD11B1 (0.51) | PAX8HSD11B1 | |
| SCHEMBL5616614 | 0.76 | IKBKB (0.51) | GRM2BTK | |
| SCHEMBL4635248 | 0.76 | HCRTR1 (0.45) | HSD11B1HCRTR1HCRTR2 | |
| SCHEMBL4636549 | 0.75 | CPS1 (0.53) | — | |
| SCHEMBL4635404 | 0.72 | PLA2G7 (0.60) | HSD11B1 | |
| SCHEMBL4635281 | 0.72 | HPGD (0.58) | FASNHSD11B1 | |
| SCHEMBL28142061 | 0.72 | IKBKB (0.48) | GRM2BTK | |
| SCHEMBL28797308 | 0.71 | IKBKB (0.43) | BTK | |
| SCHEMBL4635371 | 0.71 | EPHX2 (0.60) | PAX8HSD11B1 | |
| SCHEMBL4898713 | 0.71 | HCRTR1 (0.57) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931633-A2 | DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007029086-A2 | DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |