SCHEMBL5616614

SCHEMBL5616614

NC(=O)c1ccc(F)cc1-c1ccc(F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 6/20 0.51
CHUK O15111 4/20 0.51
BTK Q06187 3/20 0.48
MEN1 O00255 1/20 0.46
JAK2 O60674 1/20 0.46
EIF2AK2 P19525 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
BCAT2 O15382 1/20 0.46
GRM2 Q14416 3/20 0.45
PTGS1 P23219 1/20 0.45
CDC7 O00311 2/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
PLK4 O00444 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28142061 0.91 IKBKB (0.48) IKBKBCHUKBTKMEN1JAK2
SCHEMBL5616388 0.90 GRM2 (0.48) IKBKBCHUKBTKBCAT2GRM2
SCHEMBL5616523 0.90 CASP1 (0.46) IKBKBCHUKMAP4K4
SCHEMBL1927478 0.89 BCAT2 (0.61) IKBKBCHUKBCAT2GRM2
SCHEMBL16741757 0.87 IKBKB (0.51) IKBKBCHUKBTKMEN1JAK2
SCHEMBL23367143 0.87 CASP1 (0.49) IKBKBCHUKBTKMAP4K4
SCHEMBL4739551 0.87 TAAR1 (0.47) IKBKBCHUKBTKMEN1JAK2
SCHEMBL4067434 0.86 GRM2 (0.55) IKBKBCHUKBTKMEN1JAK2
SCHEMBL22320212 0.86 IDO1 (0.44) IKBKBCHUKBTKMEN1JAK2
SCHEMBL5616629 0.85 IKBKB (0.51) IKBKBCHUKBTKMEN1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007071656-A1 METHOD FOR CONTROLLING RUSTING IN LEGUMINOUS PLANTS BASF AKTIENGESELLSCHAFT (DE) 2007-06-28 WO disclosed