SCHEMBL4635172

SCHEMBL4635172

CCn1c2ccccc2c2cc(C(c3ccc(N(C)C)cc3)c3ccc(N(C)C)cc3)ccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.51
KDM4E B2RXH2 7/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
HTT P42858 3/20 0.51
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
MAPK1 P28482 2/20 0.51
HBB P68871 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
DRD3 P35462 1/20 0.46
SRC P12931 2/20 0.46
LMNA P02545 5/20 0.46
RORC P51449 1/20 0.46
NPY5R Q15761 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
POLB P06746 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14526612 0.90 MAPT (0.49) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL253310 0.89 MAPT (0.63) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL3156176 0.87 MAPT (0.58) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL7642433 0.84 MAPT (0.61) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL2108365 0.81 MAPT (0.55) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL4635069 0.80 KDM4E (0.54) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL9500947 0.79 ALDH1A1 (0.43) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL9657922 0.78 ALDH1A1 (0.48) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL9656627 0.78 ALDH1A1 (0.48) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL8232713 0.78 MAPT (0.61) MAPTKDM4EMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934561-B1 IMPROVED TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORP (US) 2018-11-07 EP claimed
US-20080269050-A1 Time/Temperature Indicators SUN CHEMICAL CORPORATION (US) 2008-10-30 US claimed
EP-1934561-A1 IMPROVED TIME/TEMPERATURE INDICATORS Sun Chemical Corporation (US) 2008-06-25 EP claimed
WO-2007035365-A1 IMPROVED TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2007-03-29 WO claimed
WO-2006091466-A1 NOVEL TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2006-08-31 WO claimed
WO-2006091465-A1 TIME/TEMPERATURE INDICATORS, THEIR PREPARATION AND USE SUN CHEMICAL CORPORATION (US) 2006-08-31 WO claimed
WO-2006091464-A1 IMPROVED TIME/ TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2006-08-31 WO claimed
EP-1934561-B1 IMPROVED TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORP (US) 2018-11-07 EP disclosed
US-20080269050-A1 Time/Temperature Indicators SUN CHEMICAL CORPORATION (US) 2008-10-30 US disclosed
WO-2006091465-A1 TIME/TEMPERATURE INDICATORS, THEIR PREPARATION AND USE SUN CHEMICAL CORPORATION (US) 2006-08-31 WO disclosed