Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253310 | 0.91 | MAPT (0.63) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL1921288 | 0.89 | MAPT (0.65) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL29643271 | 0.89 | MAPT (0.65) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL3156176 | 0.87 | MAPT (0.58) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL27825721 | 0.81 | MAPT (0.67) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL1921261 | 0.81 | PTGER4 (0.72) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL4635172 | 0.81 | MAPT (0.51) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL8232713 | 0.80 | MAPT (0.61) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL14037008 | 0.80 | MAPT (0.57) | MAPTTP53KDM4ETDP1MEN1 | |
| SCHEMBL10666862 | 0.80 | TP53 (0.60) | MAPTTP53KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211118-B2 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-01 | — | — | US | claimed |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | claimed |
| US-20130129648-A1 | SILICONE BASED COSMETIC COMPOSITIONS AND USES THEREOF | L'OREAL (FR) | 2013-05-23 | — | — | US | disclosed |
| US-8163037-B2 | Methods and kits for providing lift and then a permanent color to hair | L'OREAL (FR) | 2012-04-24 | — | — | US | disclosed |
| US-20110203605-A1 | METHODS AND KITS FOR PROVIDING LIFT AND THEN A PERMANENT COLOR TO HAIR | L'OREAL (FR) | 2011-08-25 | — | — | US | disclosed |
| US-7611544-B2 | Methods of artificially coloring hair | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | L'OREAL S.A. (FR) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | KRT18, KMO, KRTCAP2 | MAPT 174/4885TP53 2041/4885KDM4E 936/4885 |
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | HDAC10, RARA, PRDM7 | MAPT 2824/4885TP53 1613/4885KDM4E 936/4885 |
| US-20110203605-A1 | METHODS AND KITS FOR PROVIDING LIFT AND THEN A PERMANENT COLOR TO HAIR | ALDH1A3, COXFA4L2, LDHB | MAPT 3905/4885TP53 1239/4885KDM4E 2245/4885 |
| US-20130129648-A1 | SILICONE BASED COSMETIC COMPOSITIONS AND USES THEREOF | SMS, SMOX, SRM | MAPT 4047/4885TP53 310/4885KDM4E 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.