SCHEMBL4635568

SCHEMBL4635568

CCC1(CS(=O)(=O)c2ccc(C)cc2)COC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 3/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.38
CTSK P43235 1/20 0.38
MCHR1 Q99705 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CRBN Q96SW2 1/20 0.38
HSD17B10 Q99714 1/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
ADAM17 P78536 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16179582 0.86 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL19683450 0.85 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL155292 0.80 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL18101 0.78 STAT3 (0.37) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL8152528 0.77 ALDH1A1 (0.38) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL11637351 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL8653633 0.73 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL27991591 0.73 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL10950116 0.73 STAT3 (0.36) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL690833 0.72 STAT3 (0.40) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235016-B1 A FERROELECTRIC ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2019-04-17 EP disclosed
CN-107438648-A A kind of ferroelectricity adhesive composition 汉高股份有限及两合公司 2017-12-05 CN disclosed
US-20170306190-A1 FERROELECTRIC ADHESIVE COMPOSITION Henkel IP & Holding GmbH (DE) 2017-10-26 US disclosed
EP-3235016-A1 A FERROELECTRIC ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2017-10-25 EP disclosed
WO-2016097077-A1 A FERROELECTRIC ADHESIVE COMPOSITION HENKEL AG & CO. KGAA (DE) 2016-06-23 WO disclosed
US-20140295200-A1 SELECTIVE COATING OF EXPOSED COPPER ON SILVER-PLATED COPPER Henkel IP & Holding GmbH (DE) 2014-10-02 US disclosed
US-7452943-B2 Polymer compounds containing oxetane and styrenic functionality NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2008-11-18 US disclosed
EP-1958943-A1 Oxetane compounds containing styrenic functionality National Starch and Chemical Investment Holding Corporation (US) 2008-08-20 EP disclosed
EP-1620488-B1 ADHESIVE COMPOSITIONS CONTAINING HYBRID OXETANE COMPOUNDS NAT STARCH CHEM INVEST (US) 2008-06-18 EP disclosed
US-7319132-B2 Polymer compounds containing oxetane and maleimide functionality NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2008-01-15 US disclosed
US-20050192446-A1 Polymer compounds containing oxetane and styrenic functionality NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2005-09-01 US disclosed
WO-2004101541-A1 OXETANE COMPOUNDS CONTAINING STYRENIC FUNCTIONALITY NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2004-11-25 WO disclosed
WO-2004101542-A1 OXETANE COMPOUNDS CONTAINING CINNAMYL FUNCTIONALITY NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2004-11-25 WO disclosed
WO-2004101550-A1 OXETANE COMPOUNDS CONTAINING MALEIMIDE FUNCTIONALITY NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2004-11-25 WO disclosed
WO-2004101646-A1 ADHESIVE COMPOSITIONS CONTAINING HYBRID OXETANE COMPOUNDS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2004-11-25 WO disclosed
US-20040225070-A1 Oxetane compounds containing maleimide functionality HENKEL AG & CO. KGAA (DE) 2004-11-11 US disclosed
US-20040225074-A1 Adhesive compositions containing hybrid oxetane compounds HENKEL AG & CO. KGAA (DE) 2004-11-11 US disclosed
US-20040225081-A1 Oxetane compounds containing cinnamyl functionality HENKEL AG & CO. KGAA (DE) 2004-11-11 US disclosed
US-20040225071-A1 Oxetane compounds containing styrenic functionality HENKEL AG & CO. KGAA (DE) 2004-11-11 US disclosed
US-6753434-B1 CURABLE; CATIONIC AND ANIONIC RING OPENING OR FREE RADICAL POLYMERIZABLE NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2004-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040225071-A1 Oxetane compounds containing styrenic functionality OXER1, OXGR1, TET1 ALDH1A1 2304/4885CYP3A4 249/4885CYP2C9 213/4885
US-20040225081-A1 Oxetane compounds containing cinnamyl functionality DUOX2, OXER1, OXGR1 ALDH1A1 2461/4885CYP3A4 101/4885CYP2C9 115/4885
US-20050192446-A1 Polymer compounds containing oxetane and styrenic functionality OXGR1, OXER1, TET1 ALDH1A1 2291/4885CYP3A4 453/4885CYP2C9 445/4885
US-20040225070-A1 Oxetane compounds containing maleimide functionality OXGR1, DUOX2, JMJD6 ALDH1A1 2841/4885CYP3A4 121/4885CYP2C9 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.