SCHEMBL155292

SCHEMBL155292

Cc1ccc(S(=O)(=O)CC2(C)COC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 4/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.41
ELANE P08246 1/20 0.41
PRTN3 P24158 1/20 0.41
CTSK P43235 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CRBN Q96SW2 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12375436 0.85 PLCG1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL4635568 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL16179582 0.79 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL12375435 0.79 CA1 (0.44) CA12CA1CA2CA3CA6
SCHEMBL277105 0.77 KMT2A (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL2854265 0.76 EPHX1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL19106783 0.74 CA12 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL11637351 0.71 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL3698657 0.71 CA12 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL7814512 0.71 KMT2A (0.39) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103463-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-16 US disclosed
US-20260055105-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
US-12410168-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-12331049-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-17 US disclosed
US-12331050-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-17 US disclosed
US-RE50455-E1 Pyrazolopyridine derivative having GLP-1 receptor agonist effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-10 US disclosed
US-20250092041-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-03-20 US disclosed
US-12187724-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-01-07 US disclosed
US-20250002494-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-01-02 US disclosed
US-20240262824-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-08 US disclosed
US-20040225074-A1 Adhesive compositions containing hybrid oxetane compounds HENKEL AG & CO. KGAA (DE) 2004-11-11 US disclosed
US-20040225070-A1 Oxetane compounds containing maleimide functionality HENKEL AG & CO. KGAA (DE) 2004-11-11 US disclosed
US-20040225081-A1 Oxetane compounds containing cinnamyl functionality HENKEL AG & CO. KGAA (DE) 2004-11-11 US disclosed
US-6753434-B1 CURABLE; CATIONIC AND ANIONIC RING OPENING OR FREE RADICAL POLYMERIZABLE NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2004-06-22 US disclosed
US-20040048957-A1 Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups OMNOVA SOLUTIONS INC. 2004-03-11 US disclosed
EP-1389224-A2 POLYMERIC SURFACTANTS DERIVED FROM CYCLIC MONOMERS HAVING PENDANT FLUORINATED CARBON GROUPS Omnova Soltions Inc (US) 2004-02-18 EP disclosed
US-6660828-B2 Powder coating; fluorinated polyoxetanes; addition-condensation copolymer OMNOVA SOLUTIONS INC. 2003-12-09 US disclosed
US-20030109662-A1 Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups DEUTSCHE BANK TRUST COMPANY AMERICAS 2003-06-12 US disclosed
US-20030092862-A1 Fluorinated short carbon atom side chain and polar group containing polymer, and flow, or leveling, or wetting agents thereof OMNOVA SOLUTIONS INC. 2003-05-15 US disclosed
WO-2002092660-A2 POLYMERIC SURFACTANTS DERIVED FROM CYCLIC MONOMERS HAVING PENDANT FLUORINATED CARBON GROUPS OMNOVA SOLTIONS INC (US) 2002-11-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410168-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect GLP1R, GPR119, GIPR ALDH1A1 2311/4885CYP3A4 2881/4885CYP2C9 3021/4885
US-20040225081-A1 Oxetane compounds containing cinnamyl functionality DUOX2, OXER1, OXGR1 ALDH1A1 2461/4885CYP3A4 101/4885CYP2C9 115/4885
US-12331049-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect GLP1R, GPR119, GIPR ALDH1A1 2311/4885CYP3A4 2881/4885CYP2C9 3021/4885
US-20260103463-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GPR119, GIPR ALDH1A1 2886/4885CYP3A4 1988/4885CYP2C9 1148/4885
US-12187724-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect GLP1R, GPR119, GIPR ALDH1A1 2311/4885CYP3A4 2881/4885CYP2C9 3021/4885
US-20250002494-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GPR119, GIPR ALDH1A1 2311/4885CYP3A4 2881/4885CYP2C9 3021/4885
US-20240262824-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GPR119, GIPR ALDH1A1 2311/4885CYP3A4 2881/4885CYP2C9 3021/4885
US-20260055105-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GIPR, GPR119 ALDH1A1 2878/4885CYP3A4 2193/4885CYP2C9 2231/4885
US-12331050-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect GLP1R, GPR119, GIPR ALDH1A1 2311/4885CYP3A4 2881/4885CYP2C9 3021/4885
US-20250092041-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GPR119, GIPR ALDH1A1 2099/4885CYP3A4 2648/4885CYP2C9 3500/4885
US-20040225070-A1 Oxetane compounds containing maleimide functionality OXGR1, DUOX2, JMJD6 ALDH1A1 2841/4885CYP3A4 121/4885CYP2C9 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.