Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | ADSS2 | P30520 | 1/20 | 0.47 |
| ▸ | IGF2R | P11717 | 4/20 | 0.46 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.43 |
| ▸ | UMPS | P11172 | 6/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15299088 | 0.76 | EPHX2 (0.41) | — | |
| SCHEMBL30189347 | 0.75 | FBP1 (1.00) | FBP1IGF2RAMDHD2UMPSDNPH1 | |
| SCHEMBL20154711 | 0.75 | FBP1 (1.00) | FBP1IGF2RAMDHD2UMPSDNPH1 | |
| SCHEMBL15722784 | 0.74 | FBP1 (0.48) | FBP1ADSS2IGF2RAMDHD2UMPS | |
| SCHEMBL14928570 | 0.74 | FBP1 (0.48) | FBP1ADSS2IGF2RAMDHD2UMPS | |
| SCHEMBL19679997 | 0.74 | FBP1 (0.48) | FBP1ADSS2UMPSDNPH1 | |
| SCHEMBL25624133 | 0.74 | FBP1 (0.48) | FBP1ADSS2IGF2RAMDHD2UMPS | |
| SCHEMBL24450790 | 0.70 | FBP1 (0.81) | FBP1IGF2RAMDHD2UMPSDNPH1 | |
| SCHEMBL187934 | 0.70 | FBP1 (0.81) | FBP1IGF2RAMDHD2UMPSDNPH1 | |
| SCHEMBL708955 | 0.70 | FBP1 (0.81) | FBP1IGF2RAMDHD2UMPSDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083465-A1 | PYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS | UNIVERSITY HEALTH NETWORK (CA) | 2008-07-17 | — | — | WO | disclosed |
| EP-1931691-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | University Health Network (CA) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007038860-A2 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007038859-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |