SCHEMBL15722784

SCHEMBL15722784

C=C1NC(=O)C=CC1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)C1O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.48
IGF2R P11717 4/20 0.40
UMPS P11172 3/20 0.40
DNPH1 O43598 1/20 0.40
ADSS2 P30520 1/20 0.39
ATIC P31939 1/20 0.38
AMDHD2 Q9Y303 1/20 0.38
HPRT1 P00492 1/20 0.37
P2RY2 P41231 1/20 0.37
P2RY6 Q15077 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722795 0.82 PGD (0.37) FBP1ADSS2P2RY2
SCHEMBL14928456 0.80 FBP1 (0.46) FBP1IGF2RUMPSDNPH1ADSS2
SCHEMBL18561552 0.78 P2RY2 (0.46) P2RY2P2RY6
SCHEMBL4635574 0.74 FBP1 (0.57) FBP1IGF2RUMPSDNPH1ADSS2
SCHEMBL25843145 0.73 FBP1 (0.46) FBP1UMPSDNPH1ATICP2RY2
SCHEMBL19679997 0.72 FBP1 (0.48) FBP1UMPSDNPH1ADSS2ATIC
SCHEMBL14928570 0.72 FBP1 (0.48) FBP1IGF2RUMPSDNPH1ADSS2
SCHEMBL25624133 0.72 FBP1 (0.48) FBP1IGF2RUMPSDNPH1ADSS2
SCHEMBL16450259 0.71 UMPS (0.48) FBP1UMPSDNPH1ATICHPRT1
SCHEMBL15277191 0.71 UMPS (0.48) FBP1UMPSDNPH1ATICHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140141067-A1 MODIFIED POLYNUCLEOTIDES ENCODING SEPTIN-4 MODERNA THERAPEUTICS, INC. (US) 2014-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140141067-A1 MODIFIED POLYNUCLEOTIDES ENCODING SEPTIN-4 SEPTIN7, SEPTIN9, SEPTIN8 FBP1 4249/4885IGF2R 3029/4885UMPS 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.