Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 7/20 | 0.45 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | ECE1 | P42892 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167222 | 1.00 | PTGS1 (0.51) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL4635618 | 1.00 | PTGS1 (0.51) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL929620 | 0.90 | PTGS1 (0.43) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL930399 | 0.86 | PTGS1 (0.41) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL27639531 | 0.86 | ALDH1A1 (0.50) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL930206 | 0.83 | PTGS1 (0.39) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL930209 | 0.82 | PTGS1 (0.38) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL19579377 | 0.82 | PTGS1 (0.58) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL197221 | 0.80 | MAPT (0.50) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL69148 | 0.80 | MAPT (0.50) | PTGS1GSTK1ALDH1A1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1933642-A1 | SALT ENHANCING COMPOUNDS AND USE | Thomas Frank Hofmann & Andreas Dunkel Inst. für Lebensmittelchemie (DE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007042274-A1 | SALT ENHANCING COMPOUNDS AND USE | THOMAS FRANK HOFMANN & ANDREAS DUNKEL (DE) | 2007-04-19 | — | — | WO | claimed |
| EP-3806661-A1 | ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF | Firmenich Incorporated (US) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020033669-A1 | ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2020-02-13 | — | — | WO | disclosed |
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-1933642-A1 | SALT ENHANCING COMPOUNDS AND USE | Thomas Frank Hofmann & Andreas Dunkel Inst. für Lebensmittelchemie (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042274-A1 | SALT ENHANCING COMPOUNDS AND USE | THOMAS FRANK HOFMANN & ANDREAS DUNKEL (DE) | 2007-04-19 | — | — | WO | disclosed |