SCHEMBL4635643

SCHEMBL4635643

CCC(O)Cc1c[nH]c([N+](=O)[O-])n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3811168 0.84 ALDH1A1 (0.39) ALDH1A1GAA
SCHEMBL17770528 0.80 L3MBTL1 (0.40) ALDH1A1
SCHEMBL6131556 0.80
SCHEMBL5051467 0.76
SCHEMBL3814861 0.76 KMT2A (0.40) ALDH1A1
Bromide SCHEMBL15646304 0.76
SCHEMBL1979723 0.74 POLB (0.34)
SCHEMBL1126343 0.74 RAB9A (0.33) ALDH1A1
SCHEMBL3194682 0.74 PTPRA (0.46)
SCHEMBL3194680 0.74 PTPRA (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014062856-A1 HYPOXIA AND HYALURONAN AND MARKERS THEREOF FOR DIAGNOSIS AND MONITORING OF DISEASES AND CONDITIONS AND RELATED METHODS HALOZYME, INC. (US) 2014-04-24 WO disclosed
EP-1931769-A2 METHOD FOR SELECTIVELY DEPLETING HYPOXIC CELLS Genetix Pharmaceuticals Inc. (US) 2008-06-18 EP disclosed
WO-2007041546-A2 METHOD FOR SELECTIVELY DEPLETING HYPOXIC CELLS GENETIX PHARMACEUTICALS, INC. (US) 2007-04-12 WO disclosed