SCHEMBL4635816

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4637044	0.88	MAPT (0.61)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL22605844	0.87	ALDH1A1 (0.63)	MAPTLMNASMN1; SMN2ALDH1A1POLB
	SCHEMBL4636292	0.86	MAPT (0.62)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL4670055	0.86	SMN1; SMN2 (0.59)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL606148	0.84	MAPT (0.57)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL4910166	0.84	LMNA (0.63)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL4635677	0.83	NOS2 (0.63)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL18547844	0.82	MAPT (0.54)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL8672067	0.82	MAPT (0.69)	NOS2NOS1NOS3MAPTLMNA
	SCHEMBL20337736	0.82	MAPT (0.56)	MAPTLMNASMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.