Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11695567 | 0.84 | HSD17B10 (0.54) | ALDH1A1MAPTHSD17B10TDP1ACHE | |
| SCHEMBL6823057 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10TDP1ACHE | |
| SCHEMBL2853294 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10TDP1ACHE | |
| SCHEMBL28248653 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10TDP1ACHE | |
| SCHEMBL1047553 | 0.80 | MAPT (0.70) | ALDH1A1MAPTHSD17B10TDP1ACHE | |
| SCHEMBL27909482 | 0.79 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TDP1ACHETSHR | |
| SCHEMBL22567 | 0.79 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TDP1ACHETSHR | |
| SCHEMBL11697720 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10TDP1ACHE | |
| SCHEMBL18138449 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTHSD17B10TDP1ACHE | |
| SCHEMBL11642537 | 0.78 | CYP19A1 (0.56) | ALDH1A1MAPTHSD17B10TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250234-A1 | FLUOROALCOHOLS AS CO-SOLVENTS FOR CHEMICAL SYNTHESIS AND METHODS FOR PRODUCING THE SAME | UNIV MISSISSIPPI (US) | 2025-08-07 | — | — | US | disclosed |
| CN-112424197-B | Difluoromethyl-phenyltriazoles as modulators of GABA receptors | 勃林格殷格翰国际公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-116535327-B | Method for improving stability of aromatic difluoromethyl compound in preparation and use | 苏州源展材料科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| US-20240376120-A1 | CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) | 2024-11-14 | — | — | US | disclosed |
| CN-117940432-A | Camptothecins compound, preparation method and application thereof | 上海弼领生物技术有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117865773-A | Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling | 大连理工大学 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023201218-A2 | FLUOROALCOHOLS AS CO-SOLVENTS FOR CHEMICAL SYNTHESIS AND METHODS FOR PRODUCING THE SAME | UNIVERSITY OF MISSISSIPPI (US) | 2023-10-19 | — | — | WO | disclosed |
| CN-116535327-A | Method for improving stability of aromatic difluoromethyl compound in preparation and use | 苏州源展材料科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-115867277-A | Novel fused heterocyclyl-carbohydrazone acyldinitrile compounds and use thereof | 韩国科学技术研究院 | 2023-03-28 | — | — | CN | disclosed |
| EP-3823967-B1 | DIFLUOROMETHYL-PHENYL TRIAZOLES AS GABA RECEPTOR MODULATORS | BOEHRINGER INGELHEIM INT (DE) | 2022-08-31 | — | — | EP | disclosed |
| CN-102153430-A | Preparation method for fluoride aromatic organic compound | JIANGSU WEIER CHEMICAL CO LTD | 2011-08-17 | — | — | CN | disclosed |
| CN-102134175-A | Preparation method of benzyl fluorine organic compound | JIANGSU WEIER CHEMICAL CO LTD | 2011-07-27 | — | — | CN | disclosed |
| WO-2008003443-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
| EP-0970938-A1 | Preparation of 1,4-bis-(difluoromethyl)benzene | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-01-12 | — | — | EP | disclosed |
| US-4743703-A | Herbicidal 4-fluoroalkyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| US-4051168-A | TO FORM FLUOROALKYL AROMATIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4051168-A | TO FORM FLUOROALKYL AROMATIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-RE29153-E | HERBICIDES, INSECTICIDES | MONSANTO COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-3992378-A | HYPNOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3962440-A | Quinoxaline compounds as hypnotic agents | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250250234-A1 | FLUOROALCOHOLS AS CO-SOLVENTS FOR CHEMICAL SYNTHESIS AND METHODS FOR PRODUCING THE SAME | HAO2, CYP2F1, FUCA2 | ALDH1A1 168/4885MAPT 3852/4885HSD17B10 231/4885 |
| US-20240376120-A1 | CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, WASF2, LITAF | ALDH1A1 795/4885MAPT 4266/4885HSD17B10 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.