Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142624 | 0.89 | PPIA (0.40) | KMT2AMEN1JAK2JAK1TYK2 | |
| SCHEMBL11372591 | 0.85 | KMT2A (0.41) | KMT2AMEN1JAK2JAK1TYK2 | |
| SCHEMBL4150579 | 0.85 | TLR7 (0.39) | KMT2AMEN1RAB9APPIAATM | |
| SCHEMBL13774578 | 0.83 | MEN1 (0.47) | KMT2AMEN1JAK2JAK1TYK2 | |
| SCHEMBL14034291 | 0.83 | ESR1 (0.43) | KMT2AMEN1JAK2JAK1TYK2 | |
| SCHEMBL4908017 | 0.82 | GPBAR1 (0.48) | KMT2AMEN1TLR7TDP1CYP3A4 | |
| SCHEMBL4158322 | 0.81 | ATM (0.37) | KMT2AMEN1JAK2JAK1TYK2 | |
| SCHEMBL9653358 | 0.79 | KMT2A (0.41) | KMT2AMEN1PPIATLR7TDP1 | |
| SCHEMBL4912349 | 0.77 | TLR7 (0.46) | KMT2AMEN1RAB9ATLR7LMNA | |
| SCHEMBL7608144 | 0.77 | PSMB1 (0.41) | RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |