Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909640 | 0.89 | TLR7 (0.43) | TLR7TRPV1GPBAR1SMN1; SMN2RAB9A | |
| SCHEMBL10794817 | 0.87 | TLR7 (0.44) | TLR7GPBAR1LMNARAB9ANPC1 | |
| SCHEMBL11372591 | 0.83 | KMT2A (0.41) | TLR7RAB9AMEN1GAAKMT2A | |
| SCHEMBL13774578 | 0.81 | MEN1 (0.47) | TLR7GPBAR1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL14034291 | 0.81 | ESR1 (0.43) | TLR7RAB9AMEN1GAAKMT2A | |
| SCHEMBL4154212 | 0.81 | NOTUM (0.41) | TLR7LMNARAB9AMEN1KMT2A | |
| SCHEMBL4908017 | 0.80 | GPBAR1 (0.48) | TLR7GPBAR1MEN1GAAKMT2A | |
| SCHEMBL4150579 | 0.80 | TLR7 (0.39) | TLR7TRPV1LMNASMN1; SMN2RAB9A | |
| SCHEMBL4142624 | 0.79 | PPIA (0.40) | TLR7RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9653077 | 0.78 | TLR7 (0.56) | TLR7MEN1KMT2ALIPEMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | RNGTT, L3MBTL4, MYB | TLR7 1460/4885TRPV1 3830/4885GPBAR1 3318/4885 |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | L3MBTL4, L3MBTL3, L3MBTL1 | TLR7 1638/4885TRPV1 3864/4885GPBAR1 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.