Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145134 | 0.88 | ATM (0.43) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL4636479 | 0.82 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL4148300 | 0.79 | ATM (0.45) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL4637507 | 0.77 | RXFP1 (0.35) | NPC1MAPTLMNACES2CES1 | |
| SCHEMBL4142542 | 0.77 | ATM (0.42) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL4636733 | 0.76 | CES2 (0.33) | CES2CES1BCHEKAT6APSMB5 | |
| SCHEMBL4636118 | 0.76 | CES2 (0.33) | NPC1RAB9ASMN1; SMN2MAPTCES2 | |
| SCHEMBL4637621 | 0.76 | CES2 (0.32) | CES2CES1BCHEKAT6APSMB5 | |
| SCHEMBL4637632 | 0.75 | CES2 (0.33) | NPC1MAPTCES2CES1BCHE | |
| SCHEMBL4146966 | 0.74 | ATM (0.34) | POLBMAPTATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |