Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160195 | 0.89 | TRPA1 (0.35) | — | |
| SCHEMBL4637507 | 0.86 | RXFP1 (0.35) | CES2BCHECES1KAT6ACTSS | |
| SCHEMBL4637621 | 0.85 | CES2 (0.32) | CES2BCHECES1KAT6APSMB5 | |
| SCHEMBL4637632 | 0.84 | CES2 (0.33) | CES2BCHECES1KAT6A | |
| SCHEMBL4636754 | 0.83 | ALDH1A1 (0.32) | CES2BCHECES1KAT6A | |
| SCHEMBL4636118 | 0.81 | CES2 (0.33) | CES2BCHECES1KAT6ACTSS | |
| SCHEMBL4636197 | 0.78 | ALDH2 (0.34) | CTSSP2RX7DHODH | |
| SCHEMBL4637022 | 0.76 | NPC1 (0.41) | CES2BCHECES1KAT6APSMB5 | |
| SCHEMBL4636792 | 0.76 | CYP11B1 (0.35) | CTSSP2RX7DHODH | |
| SCHEMBL4157453 | 0.76 | TRPA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |