Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636754 | 0.94 | ALDH1A1 (0.32) | CES2BCHECES1KAT6AALDH1A1 | |
| SCHEMBL4637507 | 0.92 | RXFP1 (0.35) | CES2BCHECES1KAT6ANPC1 | |
| SCHEMBL4151007 | 0.88 | TRPA1 (0.33) | NPC1MAPT | |
| SCHEMBL4636118 | 0.86 | CES2 (0.33) | CES2BCHECES1KAT6ANPC1 | |
| SCHEMBL4636733 | 0.84 | CES2 (0.33) | CES2BCHECES1KAT6A | |
| SCHEMBL4636710 | 0.84 | CYP11B1 (0.33) | ALDH1A1GPBAR1 | |
| SCHEMBL4636185 | 0.82 | CES2 (0.33) | CES2BCHECES1KAT6A | |
| SCHEMBL4636412 | 0.82 | CES2 (0.34) | CES2BCHECES1GPBAR1 | |
| SCHEMBL4163009 | 0.82 | KMT2A (0.34) | NPC1ALDH1A1MAPT | |
| SCHEMBL4636792 | 0.81 | CYP11B1 (0.35) | MAPTGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |