Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL1408899 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL1408901 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28281596 | 0.91 | GPR84 (0.62) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Phosphoric Acid SCHEMBL15018812 | 0.89 | GPR84 (0.75) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Phosphoric Acid SCHEMBL15018495 | 0.89 | GPR84 (0.75) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28878630 | 0.87 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hexanoate SCHEMBL9461651 | 0.87 | AKR1B1 (0.80) | LMNATSHRSLC22A6GPR84FFAR1 | |
| Succinic Acid SCHEMBL285626 | 0.86 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2244299 | 0.86 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL8941691 | 0.86 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077871-A1 | SALTS OF TEGASEROD | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | claimed |
| EP-1939176-A1 | Salts of Tegaserod | Novartis AG (CH) | 2008-07-02 | — | — | EP | claimed |
| CN-113993826-B | Interlayer film for laminated glass, roll, and laminated glass | 积水化学工业株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-109384986-A | A kind of 3D printing easy spraying polyethylene composition and preparation method thereof | 中国石化扬子石油化工有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-107208118-A | The non-natural microorganism of energy efficiency with raising | 基因组股份公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2008077871-A1 | SALTS OF TEGASEROD | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| EP-1939176-A1 | Salts of Tegaserod | Novartis AG (CH) | 2008-07-02 | — | — | EP | disclosed |