Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.69 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28620198 | 0.96 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Succinic Acid SCHEMBL28408477 | 0.96 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Succinic Acid SCHEMBL1643228 | 0.96 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Succinic Acid SCHEMBL28620196 | 0.96 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Succinic Acid SCHEMBL14881109 | 0.87 | OR51E2 (0.59) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Succinic Acid SCHEMBL3039741 | 0.86 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Adipic Acid SCHEMBL4637028 | 0.86 | LMNA (0.73) | LMNATSHRMEN1BLMKMT2A | |
| Alpha-Ketoglutaric Acid SCHEMBL28457662 | 0.85 | EGLN1 (0.78) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Succinic Acid SCHEMBL27747949 | 0.85 | FFAR3 (0.72) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| Succinic Acid SCHEMBL4269135 | 0.83 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260130856-A1 | LIPOSOME COMPOSITIONS FOR DELIVERY OF COMPOUNDS AND METHODS THEREOF | NANOTECH PHARMA INC (US) | 2026-05-14 | — | — | US | claimed |
| EP-4601621-A1 | LIPOSOME COMPOSITIONS FOR DELIVERY OF COMPOUNDS AND METHODS THEREOF | Nanotech Pharma Inc. (US) | 2025-08-20 | — | — | EP | claimed |
| US-20240197863-A1 | LIQUID SIX COMBINED VACCINE COMPOSITION | KM BIOLOGICS CO., LTD. (JP) | 2024-06-20 | — | — | US | claimed |
| WO-2024081910-A1 | LIPOSOME COMPOSITIONS FOR DELIVERY OF COMPOUNDS AND METHODS THEREOF | NANOTECH PHARMA INC. (US) | 2024-04-18 | — | — | WO | claimed |
| EP-4327820-A1 | LIQUID SEXTUPLE VACCINE COMPOSITION | KM Biologics Co., Ltd. (JP) | 2024-02-28 | — | — | EP | claimed |
| CN-117177768-A | Composition of 6 mixed liquid vaccines | KM生物医药股份公司 | 2023-12-05 | — | — | CN | claimed |
| CN-113414167-B | Surfactant, preparation method thereof and ceramic part cleaning method | 北京北方华创微电子装备有限公司 | 2023-08-18 | — | — | CN | claimed |
| WO-2022267916-A1 | SURFACTANT, PREPARATION METHOD THEREFOR, AND METHOD FOR CLEANING CERAMIC PART | 北京北方华创微电子装备有限公司 | 2022-12-29 | — | — | WO | claimed |
| CN-113414167-A | Surfactant, preparation method thereof and ceramic part cleaning method | 北京北方华创微电子装备有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-110526425-A | A kind of ENERGY-SAVING AGENT FOR applied to boiler water processing | QINGDAO KERUN BIOTECHNOLOGY CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-109475125-A | INTERACTION BETWEEN ANTIMICROBIAL QUATERNARY COMPOUNDS AND ANIONIC SURFACTANTS | 埃科莱布美国股份有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-107298708-A | Glucagon-like peptide-1 (GLP-1) analogue with ether bond and application thereof | 中国药科大学 | 2017-10-27 | — | — | CN | claimed |
| CN-107253985-A | The design and its application of one class New-type long-acting incretin peptide | 中国药科大学 | 2017-10-17 | — | — | CN | claimed |
| CN-107141348-A | Long-acting exenatide (Exendin-4) analogue and application thereof | 中国药科大学 | 2017-09-08 | — | — | CN | claimed |
| CN-107056928-A | One class long-actingization glucagon-like-peptide-1（GLP-1）Analog and its application | 中国药科大学 | 2017-08-18 | — | — | CN | claimed |
| CN-107056926-A | Exendin-4 analogues with ether bonds and application thereof | 中国药科大学 | 2017-08-18 | — | — | CN | claimed |
| EP-0823889-B1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCARISTA LTD (GB) | 2002-09-18 | — | — | EP | claimed |
| US-20260130856-A1 | LIPOSOME COMPOSITIONS FOR DELIVERY OF COMPOUNDS AND METHODS THEREOF | NANOTECH PHARMA INC (US) | 2026-05-14 | — | — | US | disclosed |
| WO-1994029242-A1 | THE BIOREMEDIATION OF SOILS CONTAINING HYDROCARBON USING CALCIUM PEROXIDE | FMC CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |
| EP-0220657-B1 | CONJUGATE OF 9-(2-HYDROXYETHOXYMETHYL)-GUANINE WITH LACTOSAMINATED HUMAN ALBUMIN, PROCESS FOR THE PEPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | LABORATORI BALDACCI Spa (IT) | 1991-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260130856-A1 | LIPOSOME COMPOSITIONS FOR DELIVERY OF COMPOUNDS AND METHODS THEREOF | SGMS2, SGMS1, LIPA | LMNA 377/4885EGLN1 879/4885ALKBH5 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.