Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 13/20 | 0.39 |
| ▸ | CA9 | Q16790 | 13/20 | 0.39 |
| ▸ | CA1 | P00915 | 11/20 | 0.39 |
| ▸ | CA2 | P00918 | 11/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479694 | 0.81 | LMNA (0.67) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11399951 | 0.79 | LMNA (0.64) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL15760447 | 0.78 | LMNA (0.59) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL14340500 | 0.78 | LMNA (0.60) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11396051 | 0.78 | LMNA (0.62) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11397642 | 0.78 | LMNA (0.62) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11393256 | 0.77 | LMNA (0.61) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL18798671 | 0.77 | LMNA (0.57) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11397990 | 0.77 | LMNA (0.61) | LMNAKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11400022 | 0.77 | LMNA (0.61) | LMNAKDM4ECYP1A2GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939186-A1 | 5-Fluorouracil derivatives and their use for the treatment of cancer | Sulfidris S.r.l. (IT) | 2008-07-02 | — | — | EP | claimed |
| EP-1939186-A1 | 5-Fluorouracil derivatives and their use for the treatment of cancer | Sulfidris S.r.l. (IT) | 2008-07-02 | — | — | EP | disclosed |