Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731118 | 0.80 | SFRP1 (0.48) | SFRP1WNT3 | |
| SCHEMBL4637349 | 0.78 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL6100030 | 0.78 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL4730694 | 0.76 | SFRP1 (0.63) | SFRP1 | |
| SCHEMBL4638020 | 0.74 | HTR2A (0.47) | SFRP1WNT3 | |
| SCHEMBL4638272 | 0.73 | SFRP1 (0.59) | SFRP1WNT3 | |
| SCHEMBL6102960 | 0.71 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL4617933 | 0.71 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL28218046 | 0.67 | — | — | |
| SCHEMBL4617745 | 0.67 | SFRP1 (1.00) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |