Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SFRP1 | Q8N474 | 15/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | WNT3 | P56703 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638272 | 0.83 | SFRP1 (0.59) | SFRP1WNT3 | |
| SCHEMBL4731118 | 0.77 | SFRP1 (0.48) | SFRP1WNT3 | |
| SCHEMBL4637352 | 0.74 | SFRP1 (0.63) | SFRP1WNT3 | |
| SCHEMBL4730694 | 0.73 | SFRP1 (0.63) | SFRP1 | |
| SCHEMBL4638015 | 0.72 | SFRP1 (0.84) | SFRP1WNT3 | |
| SCHEMBL12384479 | 0.65 | ALDH1A1 (0.56) | HTR2AHTR2CKCNH2KMT2A | |
| SCHEMBL12859265 | 0.65 | KMT2A (0.64) | HTR2AHTR2CKCNH2KMT2A | |
| SCHEMBL4308106 | 0.65 | ALDH1A1 (0.59) | HTR2AHTR2CKCNH2KMT2A | |
| SCHEMBL6583840 | 0.65 | HTR2A (1.00) | HTR2AHTR2CKCNH2 | |
| SCHEMBL4618251 | 0.64 | SFRP1 (1.00) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |