Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321077 | 0.98 | L3MBTL1 (0.31) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL27802912 | 0.79 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1HPGDMAPK1 | |
| SCHEMBL4591978 | 0.77 | L3MBTL1 (0.34) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1428601 | 0.76 | CHRM2 (0.33) | L3MBTL1ALDH1A1HTTMAPK1 | |
| SCHEMBL4592224 | 0.74 | L3MBTL1 (0.32) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5648812 | 0.73 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1HPGDMAPK1 | |
| SCHEMBL3861075 | 0.73 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1HPGDMAPK1 | |
| SCHEMBL9936387 | 0.72 | L3MBTL1 (0.31) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL27823606 | 0.71 | ALDH1A1 (0.32) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7631553 | 0.71 | OPRM1 (0.32) | L3MBTL1ALDH1A1HPGDFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | claimed |
| CN-109608524-A | It is a kind of to have both DPP-4 inhibition and polypeptide derivative, preparation and the application of GLP1R Activation Activity | 李泉 | 2019-04-12 | — | — | CN | disclosed |