Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222227 | 0.73 | CDK5 (0.53) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| SCHEMBL219729 | 0.70 | BCL9 (0.49) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| 3,6-Dimethoxy Kaempferol SCHEMBL30707828 | 0.69 | TUBB4A (0.83) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| 3,6-Dimethoxy Kaempferol SCHEMBL1156264 | 0.69 | TUBB4A (0.83) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| SCHEMBL24994535 | 0.68 | ABCB1 (0.65) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| SCHEMBL29782758 | 0.68 | ABCB1 (0.72) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| SCHEMBL29782768 | 0.68 | ABCB1 (0.72) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| Isokaempferide SCHEMBL1628023 | 0.68 | POLH (1.00) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| Isokaempferide SCHEMBL29721227 | 0.68 | POLH (1.00) | POLBKDM4ECYP3A4CYP2D6APEX1 | |
| SCHEMBL31238141 | 0.68 | KDM4E (0.68) | POLBKDM4ECYP3A4CYP2D6APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781235-A4 | ANTI-HYPERSENSITIVE INFLAMMATION AND ANTI-ALLERGY ACTIVITIES OF ZINGIBER ZERUMBET (L.) SMITH | WHOLESOME LIFE SCIENCE CO LTD (TW) | 2008-07-02 | — | — | EP | claimed |
| EP-1781235-A1 | ANTI-HYPERSENSITIVE INFLAMMATION AND ANTI-ALLERGY ACTIVITIES OF ZINGIBER ZERUMBET (L.) SMITH | Wholesome Life Science Co., Ltd. (TW) | 2007-05-09 | — | — | EP | claimed |
| US-20060083799-A1 | Anti-hypersensitive inflammation and anti-allergy activities of Zingiber zerumbet (L.) Smith | WHOLESOME LIFE SCIENCE CO., LTD. | 2006-04-20 | — | — | US | claimed |
| WO-2006020246-A1 | ANTI-HYPERSENSITIVE INFLAMMATION AND ANTI-ALLERGY ACTIVITIES OF ZINGIBER ZERUMBET (L.) SMITH | LIN TSUNG-CHUNG (US) | 2006-02-23 | — | — | WO | claimed |