Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663384 | 0.85 | GAA (0.52) | GAAALDH1A1PDK1PDK2PDK3 | |
| SCHEMBL3792624 | 0.85 | RAPGEF4 (0.40) | CYP1A2CYP2A6LMNATSHRGAA | |
| SCHEMBL2101475 | 0.83 | ADRA2A (0.37) | CYP1A2CYP2A6LMNATSHRGAA | |
| SCHEMBL9228613 | 0.83 | KCNH2 (0.46) | LMNAGAAALDH1A1PDK1PDK2 | |
| SCHEMBL21290593 | 0.83 | ADRA2A (0.37) | CYP1A2CYP2A6LMNATSHRGAA | |
| SCHEMBL14608489 | 0.83 | CYP1A2 (0.35) | CYP1A2CYP2A6LMNATSHRGAA | |
| SCHEMBL11802445 | 0.83 | TSHR (0.50) | LMNATSHRGAAALDH1A1PDK1 | |
| SCHEMBL101764 | 0.83 | ALDH1A1 (0.52) | CYP1A2CYP2A6TSHRGAAADRA2A | |
| SCHEMBL11661447 | 0.79 | SMN1; SMN2 (0.44) | CYP1A2LMNATSHRALDH1A1CYP2D6 | |
| SCHEMBL11660113 | 0.79 | KCNH2 (0.49) | TSHRGAAADRA1ATAAR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343749-A2 | METHOD FOR PRODUCING PRIMARY AND SECONDARY AMINES BY HYDROGENATING NITRILES AND IMINES | Degussa AG (DE) | 2003-09-17 | — | — | EP | claimed |
| WO-2002051791-A2 | METHOD FOR PRODUCING PRIMARY AND SECONDARY AMINES BY HYDROGENATING NITRILES AND IMINES | DEGUSSA AG (DE) | 2002-07-04 | — | — | WO | claimed |
| CN-117720494-A | Preparation method and application of novel coumarin derivative plant growth regulator and composition | 贵州工业职业技术学院 | 2024-03-19 | — | — | CN | disclosed |
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | GAIN THERAPEUTICS SA (CH) | 2023-05-04 | — | — | US | disclosed |
| CN-111039940-B | Aurora A kinase inhibitor, preparation method, pharmaceutical composition and application thereof | 北京鑫开元医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114302874-A | Indole carboxamide derivatives and pharmaceutical compositions comprising same | 国际药品株式会社 | 2022-04-08 | — | — | CN | disclosed |
| EP-3702355-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS CONTAINING PYRIMIDINE, THE PREPARATION AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| CN-109535132-B | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2021-07-20 | — | — | CN | disclosed |
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | disclosed |
| US-10993439-B2 | Mesoionic imidazopyridines as insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-04 | — | — | US | disclosed |
| EP-1343749-A2 | METHOD FOR PRODUCING PRIMARY AND SECONDARY AMINES BY HYDROGENATING NITRILES AND IMINES | Degussa AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002051791-A2 | METHOD FOR PRODUCING PRIMARY AND SECONDARY AMINES BY HYDROGENATING NITRILES AND IMINES | DEGUSSA AG (DE) | 2002-07-04 | — | — | WO | disclosed |
| US-4488993-A | Amidinoureas | WILLIAM H. RORER, INC. | 1984-12-18 | — | — | US | disclosed |
| US-4283555-A | Amidinoureas | WILLIAM H. RORER, INC. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4220658-A | Treatment of hypertension with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-02 | — | — | US | disclosed |
| US-4219567-A | ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1980-08-26 | — | — | US | disclosed |
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4076530-A | Dry photographic copying method for producing Te images | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10993439-B2 | Mesoionic imidazopyridines as insecticides | DDT, CHRM1, GRM1 | CYP1A2 660/4885CYP2A6 2898/4885LMNA 684/4885 |
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | IDUA, MAN2B1, GBA1 | CYP1A2 1487/4885CYP2A6 2127/4885LMNA 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.