Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392363 | 0.95 | L3MBTL1 (0.53) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL28310663 | 0.84 | CTNNB1 (0.53) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL3943135 | 0.82 | HDAC1 (0.65) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL4637871 | 0.82 | HSD17B3 (0.62) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL4186280 | 0.82 | HDAC3 (0.59) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL1361623 | 0.81 | GSK3B (0.59) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL30517873 | 0.81 | GSK3B (0.59) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL10632540 | 0.81 | HSD17B3 (0.64) | CTNNB1ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL2979252 | 0.79 | KDM4E (0.59) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL4569137 | 0.79 | PARP1 (0.59) | CTNNB1CA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |