Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 4/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447471 | 0.92 | SIRT6 (1.00) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL4221243 | 0.87 | KMT2A (0.67) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL3569406 | 0.86 | LMNA (1.00) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL7155984 | 0.84 | POLB (0.84) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL56547 | 0.83 | MAPT (1.00) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL6414948 | 0.83 | MAPT (1.00) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL15271381 | 0.83 | SIRT6 (0.81) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL6151230 | 0.83 | SIRT6 (0.81) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL6151538 | 0.83 | MAPT (1.00) | SIRT6LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL11171262 | 0.82 | SIRT6 (0.81) | SIRT6LMNAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |