SCHEMBL4638388

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4638407	0.89	KDM4E (0.41)	RAB9AAGERPLK1KMT2AMAPK1
	SCHEMBL4638721	0.89	RAB9A (0.38)	RAB9AAGERPLK1KMT2AMAPK1
	SCHEMBL4888666	0.85	CACNA1G (0.43)	RAB9AAGERKMT2AMAPK1HTT
	SCHEMBL4639356	0.85	CACNA1G (0.43)	RAB9AAGERKMT2AMAPK1HTT
	SCHEMBL4638620	0.85	CACNA1G (0.43)	RAB9AAGERKMT2AMAPK1HTT
	SCHEMBL4639622	0.84	CNR1 (0.46)	KMT2AMAPK1P2RX7ALDH1A1CNR1
	SCHEMBL4639146	0.83	KMT2A (0.38)	PLK1KMT2AP2RX7MEN1USP2
	SCHEMBL4638567	0.81	AVPR2 (0.45)	KMT2AP2RX7
	SCHEMBL2438203	0.78	AGER (0.46)	AGERKMT2AKDM4EABCB1
	SCHEMBL4638953	0.77	NR3C2 (0.44)	KMT2AHTTP2RX7MEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.