SCHEMBL4638447

SCHEMBL4638447

NC(=O)[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.52
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
USP2 O75604 1/20 0.48
SLCO1B1 Q9Y6L6 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PGD P52209 1/20 0.39
KDM4E B2RXH2 2/20 0.36
TGFBR1 P36897 1/20 0.32
OR51E2 Q9H255 1/20 0.32
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122819 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL4728437 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL2126263 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL7151302 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL1591176 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL6665411 1.00 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL1569332 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL5268306 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL2912046 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL20576207 0.92 PDE4A (0.62) PDE4ALMNAL3MBTL1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0946744-A1 NOVEL POLYMERIC COMPLEXES FOR THE TRANSFECTION OF NUCLEIC ACIDS, WITH RESIDUES CAUSING THE DESTABILISATION OF CELL MEMBRANES I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 1999-10-06 EP claimed
WO-1998022610-A1 NOVEL POLYMERIC COMPLEXES FOR THE TRANSFECTION OF NUCLEIC ACIDS, WITH RESIDUES CAUSING THE DESTABILISATION OF CELL MEMBRANES I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 1998-05-28 WO claimed
CN-118947730-A Plant treatment products and related methods 美国赛多美科技有限公司 2024-11-15 CN disclosed
CN-110678076-B Plant treatment products and related methods 美国赛多美科技有限公司 2024-07-23 CN disclosed
US-20230304998-A1 CELLULAR MATERIAL DETECTION PROBES FluoretiQ Limited (GB) 2023-09-28 US disclosed
EP-4146849-A1 CELLULAR MATERIAL DETECTION PROBES Fluoretiq Limited (GB) 2023-03-15 EP disclosed
US-10745395-B2 Compounds for their use as drugs for the treatment and/or the prevention of infection(s) caused by biofilm-forming bacteria CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-08-18 US disclosed
US-20180030047-A1 COMPOUNDS FOR THEIR USE AS DRUGS FOR THE TREATMENT AND/OR THE PREVENTION OF INFECTION(S) CAUSED BY BIOFILM-FORMING BACTERIA UNIVERSITE D'ORLEANS (FR) 2018-02-01 US disclosed
EP-3186253-A1 COMPOUNDS FOR THEIR USE AS DRUGS FOR THE TREATMENT AND/OR THE PREVENTION OF INFECTION(S) CAUSED BY BIOFILM-FORMING BACTERIA Centre National De La Recherche Scientifique (FR) 2017-07-05 EP disclosed
WO-2016030434-A1 COMPOUNDS FOR THEIR USE AS DRUGS FOR THE TREATMENT AND/OR THE PREVENTION OF INFECTION(S) CAUSED BY BIOFILM-FORMING BACTERIA CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-03-03 WO disclosed
WO-2013075227-A1 β-GLUCOCEREBROSIDASE CHAPERONES THE HOSPITAL FOR SICK CHILDREN (CA) 2013-05-30 WO disclosed
US-20080269285-A1 Novel Compounds of the Family of Iminosugars, Uses Thereof for Trewating Lysosomal Diseases, and Method for Preparing Same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-10-30 US disclosed
EP-1893201-A1 NOVEL COMPOUNDS OF THE FAMILY OF IMINOSUGARS, USES THEREOF FOR TREATING LYSOSOMAL DISEASES, AND METHOD FOR PREPARING SAME The Centre National de la Recherche Scientifique (FR) 2008-03-05 EP disclosed
WO-2006136714-A1 NOVEL COMPOUNDS OF THE FAMILY OF IMINOSUGARS, USES THEREOF FOR TREATING LYSOSOMAL DISEASES, AND METHOD FOR PREPARING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2006-12-28 WO disclosed
EP-0946744-B1 NOVEL POLYMERIC COMPLEXES FOR THE TRANSFECTION OF NUCLEIC ACIDS, WITH RESIDUES CAUSING THE DESTABILISATION OF CELL MEMBRANES IDM IMMUNO DESIGNED MOLECULES (FR) 2004-08-18 EP disclosed
EP-0946744-A1 NOVEL POLYMERIC COMPLEXES FOR THE TRANSFECTION OF NUCLEIC ACIDS, WITH RESIDUES CAUSING THE DESTABILISATION OF CELL MEMBRANES I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 1999-10-06 EP disclosed
WO-1999046243-A1 PROCESS FOR THE ENANTIOSELECTIVE SYNTHESIS OF HYDROXYPYRROLIDINES FROM AMINO ACIDS AND PRODUCTS THEREOF TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1999-09-16 WO disclosed
US-5801247-A Process for the enantioselective synthesis of hydroxypyrrolidines from amino acids and products thereof TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1998-09-01 US disclosed
WO-1998022610-A1 NOVEL POLYMERIC COMPLEXES FOR THE TRANSFECTION OF NUCLEIC ACIDS, WITH RESIDUES CAUSING THE DESTABILISATION OF CELL MEMBRANES I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 1998-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030047-A1 COMPOUNDS FOR THEIR USE AS DRUGS FOR THE TREATMENT AND/OR THE PREVENTION OF INFECTION(S) CAUSED BY BIOFILM-FORMING BACTERIA CHRM1, FPR1, NOX1 PDE4A 3784/4885LMNA 2358/4885L3MBTL1 424/4885
US-20080269285-A1 Novel Compounds of the Family of Iminosugars, Uses Thereof for Trewating Lysosomal Diseases, and Method for Preparing Same GBA1, GAA, MAN2B1 PDE4A 1704/4885LMNA 1256/4885L3MBTL1 856/4885
US-10745395-B2 Compounds for their use as drugs for the treatment and/or the prevention of infection(s) caused by biofilm-forming bacteria CHRM1, FPR1, FPR3 PDE4A 2879/4885LMNA 2341/4885L3MBTL1 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.