Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.35 |
| ▸ | CA1 | P00915 | 7/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA6 | P23280 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30755329 | 0.72 | CA2 (0.38) | CA2CA1CA9CA6CA4 | |
| SCHEMBL4616951 | 0.72 | CA2 (0.38) | CA2CA1CA9CA6CA4 | |
| SCHEMBL30988956 | 0.68 | CA2 (0.50) | CA2CA1CA9CA6CA4 | |
| SCHEMBL407413 | 0.68 | CA2 (0.50) | CA2CA1CA9CA6CA4 | |
| SCHEMBL8349565 | 0.66 | CA2 (0.54) | CA2CA1CA9CA6CA4 | |
| Hydrochloric Acid SCHEMBL3517386 | 0.66 | CA1 (0.49) | CA2CA1CA9CA6CA4 | |
| Methane SCHEMBL28850761 | 0.66 | CA2 (0.49) | CA2CA1CA9CA6CA4 | |
| SCHEMBL4662992 | 0.65 | PTGES2 (0.54) | CA2CA1CA9CA6CA4 | |
| SCHEMBL4661657 | 0.65 | CA2 (0.44) | CA2CA1CA9CA6CA4 | |
| SCHEMBL4664484 | 0.65 | LMNA (0.46) | CA2CA1CA9CA6CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | claimed |